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experimental high-throughput screening data set  (Icagen Inc)

 
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    Icagen Inc experimental high-throughput screening data set
    Experimental High Throughput Screening Data Set, supplied by Icagen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/experimental+high-throughput+screening+data+set/experimental+high+throughput+screening+data+set/pm11350250-3-4-29
    Average 90 stars, based on 1 article reviews
    experimental high-throughput screening data set - by Bioz Stars, 2026-10
    90/100 stars

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    Article Title: Retrospective analysis of an experimental high-throughput screening data set by recursive partitioning.
    Article Snippet: With the emergence of combinatorial chemistry, whether based on parallel, mixture, solution, or solid phase chemistry, it is now possible to generate large numbers of diverse or focused compound libraries.. In this paper we aim to demonstrate that it is possible to design targeted libraries by applying nonparametric statistical methods, recursive partitioning in particular, to large data sets containing thousands of compounds and their associated biological data.. Moreover, when applied to an experimental high-throughput screening (HTS) data set, our data strongly suggest that this method can improve the hit rate of our primary screens (about 4to 5-fold) while increasing screening efficiency: less than one-fifth of the complete selection needs to be screened in order to identify about 75% of all actives present.



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